Is it Possible That Fioricet can Increase the Effects of Methadone?

Methadone is a medication used to treat Opioid Use Disorder (OUD). Methadone is a long-acting full opioid agonist, and a schedule II controlled medication.

Methadone is a medication approved by the Food and Drug Administration (FDA) to treat opioid use disorder (OUD) as a medication-assisted treatment (MAT), as well as for pain management. When taken as prescribed, methadone is safe and effective. Methadone helps individuals achieve and sustain recovery and to reclaim active and meaningful lives.

Methadone is one component of a comprehensive treatment plan, which includes counseling and other behavioral health therapies to provide patients with a whole-person approach.

Fioricet contains a combination of acetaminophen, butalbital, and caffeine Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Interactions Between Methadone and butalbital

methadone ↔ butalbital

Applies to: methadone, Fioricet (acetaminophen/butalbital/caffeine)

MONITOR: The coadministration of barbiturates and methadone may result in decreased plasma concentrations of the latter. There have been case reports of patients receiving methadone maintenance treatment who performed poorly or developed withdrawal symptoms during the use of barbiturates, which generally correlated with low plasma methadone levels. The mechanism of the interaction is accelerated clearance of methadone due to induction of hepatic CYP450 enzymatic activities by barbiturates. Although the interaction has only been reported with phenobarbital and pentobarbital, it is expected to occur with all barbiturates based on their known enzyme-inducing capabilities.

MANAGEMENT: Caution is advised during concomitant therapy with these agents. Pharmacologic response to methadone should be closely monitored and the dosage adjusted accordingly, particularly following initiation, discontinuation or change of dosage of the barbiturate in patients who are stabilized on their methadone regimen. Patients should be advised to notify their caregiver if they experience possible symptoms of methadone withdrawal, including restlessness, insomnia, sweating, lacrimation, or rhinorrhea.

Other drugs that your selected drugs interact with

methadone interacts with more than 400 other drugs.

Fioricet (acetaminophen/butalbital/caffeine) interacts with more than 400 other drugs.

 

 

Buy Prescription Fioricet (Butalbital APAP Caffeine) Online

Pain can interrupt all parts of life, from work to home life. Of course, if you were in pain the last thing you want to do is go stand in line at the drugstore. While ordering Affordable Fioricet(Butalbital APAP Caffeine) online won’t allow you to leave your house, your medication will be sent directly to your door and ensuring that you are finally able to access the help that you need.

How to use Fioricet

Take this medication by mouth with or without food as directed by your doctor, usually every 4 hours as needed.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition, age, and response to treatment. This medication works best if it is used as the first signs of a headache occur. If you wait until the headache has worsened, the medication may not work as well.

If you suddenly stop using this medication, you may have withdrawal symptoms (such as nausea/vomiting, mental/mood changes, seizures). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used this medication for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if you notice increased use of this medication, a worsening of headaches, an increase in the number of headaches, the medication not working as well, or use of this medication for more than 2 headache episodes a week. Do not take more than recommended. Your doctor may need to change your medication and/or add a separate medication to prevent the headaches.

Like just about everything else out there, the price of pain medication has been rising steadily more than the years. even though you are currently on the pain prescription, then you definitely know it can cost rather a bit to keep up with your monthly prescriptions even with wellness insurance policies footing most of the bill. even though you will not have health insurance policy, then this expense becomes even a lot more of the burden. That is why numerous consumers now choose to order prescription Fioricet (Butalbital APAP Caffeine) online.

Fioricet is used to treat tension headaches that are caused by muscle contractions. It comes as a capsule and tablet form to take by mouth. One or 2 pills every 4 hours as needed. Total daily dosage should not exceed 6 pills. Extended and repeated use of this product is not recommended because of the potential for physical dependence.

Will fioricet help siatic nerve pain?

Fioricet is normally prescribed for tension and migraine headaches. It can be addicting due to the barbiturate component. It has been prescribed “off label” for other uses.

If it is the codeine type you may be better off with Tylenol with codeine for sciatic pain. I have had a patient who stated she had tried multiple pain relievers for her back pain and nothing worked.

Out of desperation one day (she had them, the plain fioricet, prescribed for headaches) she tried one for her back pain and discovered they worked better than anything for her. So, on that note, it may but it is not what it is usually indicated for.

Fioricet Blue and White Tablet
Fioricet Blue and White Tablet

Where to Buy Fioricet Online ?

When you order prescription Fioricet (Butalbital APAP Caffeine) Internet On Line our process could not be simpler, just select the Soma medicines you need, fill in our medical questionnaire, and submit your order. Our U.S Licensed Physicians will review your order and issue your prescription. Next, our U.S. Licensed Pharmacies will dispense, and FedEx your order discreetly using Next day delivery.

At BuyPrescriptionFioricet.com, you can contact us at any time either by clicking the Live Help button for a live chat session with our customer service staff. We look forward to helping you with all your medical needs, this time, and in the future.

Who Can not Buy Fioricet Online ?

Who cannot Buy Fioricet Online ?

    • If you have liver, kidney, or heart diseases, please donot take fioricet. Because fioricet contains barbiturate butalbital, it can cross the placental barrier;
    • We donot suggest you order fioricet online if you are pregnant or or in breast feeding period.   If you are pregnant, please go to your street doctors and let them to check whether you are OK to take fioricet;
    • If you are addictive to alcohol or other pain killer medicines, please donot buy fioricet online, you must find a street doctor to solve your addictive first before you order fioricet, or buy fioricet online;
    • You must complete the health questionnaires very carefull because the US licensed doctors and pharmacists will review your health questionnaires to approve your prescription or not;
    • All online pharmacies share the same blacklist. If you have paid bounced checks to any online pharmacy and you will be blacklisted by all online pharmacies. You are not allowed to order Fioricet Online;
    • We will not send you Fioricet or  Gabapentin if you have suicide thoughts

For more detail fioricet prescription instruction, you can check Wiki Fioricet. The pharmacy will also send you a instruction on fioricet usage and introduction. Please be very careful to take the fioricet within the max dosage. Never exceed the max dosages. Or you will be seriously damaged.

What is Butalbital?

Butalbital is a medication within the drug classification known as barbiturates. It is taken orally to treat a variety of mild to moderate conditions.

Barbiturates act primarily on the central nervous system (CNS) and have an intermediate duration of action compared to common over-the-counter medications.

Butalbital is most commonly combined with acetaminophen and caffeine to achieve the most desirable effects.

If you miss a dose of Butalbital, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double dose.

Butalbital is best stored at room temperature away from moisture and heat. For more drug information on Butalbital, check the packaging of the product.

What is Butalbital Used For?

Butalbital is used primarily in treating tension headaches, also known as stress headaches. These are classified as attacks that:

  • Last between 30 minutes and seven days
  • Have bilateral location, are non-pulsating, have mild or moderate intensity, and are not aggravated by activity
  • Do not cause nausea or vomiting, sensitivity to light, or sensitivity to sound

Butalbital should not be used for the treatment of migraine headaches. It is a prescription drug that should only be used on the professional medical advice of a licensed healthcare provider.

Though used mainly for treating headaches, butalbital can also be used as a sedative to treat anxiety, seizures, and, in some cases, insomnia.

Side Effects of Butalbital

There are several common and infrequent side effects of butalbital, including:

  • Decreases in reaction time
  • Loss of motor coordination or balance
  • Slowing of the speed and flow of thinking processes
  • Dizziness or lightheadedness
  • Lethargy
  • Drowsiness
  • Nausea
  • Vomiting
  • Stomach pain and cramps
  • Shallow breathing or shortness of breath due to respiratory depression

Rare side effects of butalbital include:

  • Allergic reaction and rash (skin reaction)
  • Difficulty breathing
  • Difficulty swallowing
  • Dry mouth
  • Indigestions and heartburn
  • Tinnitus
  • Leg pain or leg cramps

Butalbital in breastmilk can also cause poor feeding and vomiting in infants. If you are breast-feeding, it is best to avoid using Butalbital.

Is Butalbital Addictive?

Butalbital has a high potential for addiction and physical dependence on the drug. Tolerance to this medication, as well as other barbiturates, can occur in a relatively short time span, often leading to higher dosage and more potential for misuse. Barbiturate overdoses can occur easily due to how quickly a tolerance can develop.

Some signs of butalbital addiction include:

  • Obtaining butalbital without a prescription
  • Overuse or taking higher doses than specified in the prescription
  • Using butalbital in ways not typically prescribed, such as grinding it up into powder and snorting it, or mixing it with other drugs
  • Appearing tired, lethargic, or in a state of intoxication
  • Slurred speech, issues with coordination, and decreased mental and physical reaction times
  • Spending significant periods of time alone
  • Defensive or angry behavior when someone attempts to discuss medication usage or drug abuse
  • Problems with attention and with memory
  • Irritability, restlessness, sensitivity
  • Continuing to use butalbital despite experiencing obvious negative issues with work, school, or in their relationships with others
  • Porphyria, a buildup of natural chemicals that produce porphyrin (a compound essential for the function of hemoglobin) in the body
  • Withdrawal symptoms

Dangers Of Butalbital Addiction

A person with Butalbital addiction is likely to develop a tolerance to the drug. They may be more likely to take more Butalbital or mix it with other depressants to maintain the initial high. Combining Butalbital with alcohol, for example, can heighten the risk of respiratory depression and liver failure.

Some people experiencing opioid addiction will use Butalbital to enhance the effects of whatever drug they are taking while also conserving their supply. This is dangerous because taking Butalbital with narcotics can lead to overdose or accidental death.

Symptoms of a barbiturate overdose, such as Butalbital, include:

  • Drowsiness
  • Confusion
  • Coma
  • Respiratory depression
  • Trouble breathing
  • Persistent nausea and vomiting
  • Severe dizziness
  • Slow or slurred speech
  • Staggering
  • Ringing in the ears

If you suspect someone is overdosing, call 911 immediately. An untreated Butalbital addiction can be life-changing or fatal.

Complications that may occur from a Butalbital overdose include:

  • Head and spinal injuries from falls
  • Pneumonia from depressed gag reflex
  • Muscle damage from lying on a hard surface for an extended period of time

Misusing Butalbital can lead to long-lasting effects on your health.

Long-term and consistent use of barbiturates can lead to chronic symptoms including:

  • Irritability
  • Memory loss
  • Decreased function
  • Shifts in alertness

Butalbital Addiction Withdrawal And Detox

Butalbital addiction is likely to cause uncomfortable withdrawal symptoms when use is quickly stopped. Barbiturates like Butalbital can lead to psychological and physical dependence, meaning withdrawal symptoms will occur when the individual stops taking the drug.

These withdrawal symptoms generally occur within two to four days of stopping Butalbital use.

Withdrawal symptoms of Butalbital include:

  • Seizures
  • Psychosis
  • Tremors
  • Restlessness
  • Insomnia
  • Anxiety

If severe withdrawal symptoms go untreated or are not quickly recognized, then the following may occur:

  • Hypothermia
  • Failure of blood circulation
  • Death

Detoxification, or detox, is the procedure of clearing the body of harmful substances. Medically supervised detox can involve administering other drugs, like opioids, in small quantities to aid with the uncomfortable effects of withdrawal symptoms. Common opioids used for detoxification include methadone, buprenorphine, and naltrexone.

You must never try to detox alone. Detox is safe and effective in a medical environment where doctors and nurses can assess dosage and progress. Withdrawal symptoms can be painful, uncomfortable, and potentially life-threatening, so professional aid is necessary.

Treatment Options for Butalbital Abuse

Behavioral treatments are often necessary to change the patient’s mindset and avoid relapse for butalbital. Cognitive behavioral therapies can be done as both outpatient (from home) and inpatient (from a medical facility) treatments.

Inpatient treatment is generally more effective as the patient will have access to constant medical and professional care.

Outpatient treatment can also be problematic due to a lack of supervision and potential home factors (such as social environment) that may have contributed to butalbital abuse in the first place.

Butalbital: Common Questions and Answers

Common questions associated with Butalbital use and addiction:

What Kind of Drug is Butalbital?

Butalbital is a barbiturate drug, which is a class of CNS depressants. This class of medication acts on the central nervous system as a depressant. They are effective as anticonvulsants, but they also carry habit-forming potential. Benzodiazepines have replaced barbiturates in recent years for several types of treatment.

Is Butalbital the Same as Fioricet?

Fioricet is not the same as butalbital, but it does contain this barbiturate compound. Fioricet is a brand-name drug containing butalbital, acetaminophen, and caffeine in one oral tablet or capsule. This medication is very similar to esgic, fiorinal, orbivan, repan, margesic, phrenilin, and phenobarbital, all of which contain butalbital and some form of pain reliever.

Is Butalbital Used for Anxiety?

Though it is used primarily to treat tension headaches, butalbital can also be prescribed to treat anxiety. This was once used as a common medication to treat this condition, but it has become less prescribed in favor of benzodiazepines, which are more widely used today.

What are the Possible Side Effects of Acetaminophen, Butalbital, and Caffeine?

In addition to those listed above, possible adverse effects of the combination drug of acetaminophen, butalbital, and caffeine include:

  • Liver damage or liver disease
  • Kidney disease
  • Abdominal pain
  • Irritability
  • Constipation
  • Nervousness
  • Tremors
  • Increased urination
  • Dark urine
  • Fainting
  • Confusion
  • Rapid heart rate
  • Difficulty sleeping

Dangers Of Butalbital Addiction

A person with Butalbital addiction is likely to develop a tolerance to the drug. They may be more likely to take more Butalbital or mix it with other depressants to maintain the initial high. Combining Butalbital with alcohol, for example, can heighten the risk of respiratory depression and liver failure.

Some people experiencing opioid addiction will use Butalbital to enhance the effects of whatever drug they are taking while also conserving their supply. This is dangerous because taking Butalbital with narcotics can lead to overdose or accidental death.

Symptoms of a barbiturate overdose, such as Butalbital, include:

      • Drowsiness
      • Confusion
      • Coma
      • Respiratory depression
      • Trouble breathing
      • Persistent nausea and vomiting
      • Severe dizziness
      • Slow or slurred speech
      • Staggering
      • Ringing in the ears

If you suspect someone is overdosing, call 911 immediately. An untreated Butalbital addiction can be life-changing or fatal.

Complications that may occur from a Butalbital overdose include:

      • Head and spinal injuries from falls
      • Pneumonia from depressed gag reflex
      • Muscle damage from lying on a hard surface for an extended period of time

Misusing Butalbital can lead to long-lasting effects on your health.

Long-term and consistent use of barbiturates can lead to chronic symptoms including:

      • Irritability
      • Memory loss
      • Decreased function
      • Shifts in alertness

Butalbital Addiction Withdrawal And Detox

Butalbital addiction is likely to cause uncomfortable withdrawal symptoms when use is quickly stopped. Barbiturates like Butalbital can lead to psychological and physical dependence, meaning withdrawal symptoms will occur when the individual stops taking the drug.

These withdrawal symptoms generally occur within two to four days of stopping Butalbital use.

Withdrawal symptoms of Butalbital include:

      • Seizures
      • Psychosis
      • Tremors
      • Restlessness
      • Insomnia
      • Anxiety

If severe withdrawal symptoms go untreated or are not quickly recognized, then the following may occur:

      • Hypothermia
      • Failure of blood circulation
      • Death

Detoxification, or detox, is the procedure of clearing the body of harmful substances. Medically supervised detox can involve administering other drugs, like opioids, in small quantities to aid with the uncomfortable effects of withdrawal symptoms. Common opioids used for detoxification include methadone, buprenorphine, and naltrexone.

You must never try to detox alone. Detox is safe and effective in a medical environment where doctors and nurses can assess dosage and progress. Withdrawal symptoms can be painful, uncomfortable, and potentially life-threatening, so professional aid is necessary.

Treatment Options for Butalbital Abuse

Behavioral treatments are often necessary to change the patient’s mindset and avoid relapse for butalbital. Cognitive behavioral therapies can be done as both outpatient (from home) and inpatient (from a medical facility) treatments.

Inpatient treatment is generally more effective as the patient will have access to constant medical and professional care.

Outpatient treatment can also be problematic due to a lack of supervision and potential home factors (such as social environment) that may have contributed to butalbital abuse in the first place.

Butalbital: Common Questions and Answers

Common questions associated with Butalbital use and addiction:

What Kind of Drug is Butalbital?

Butalbital is a barbiturate drug, which is a class of CNS depressants. This class of medication acts on the central nervous system as a depressant. They are effective as anticonvulsants, but they also carry habit-forming potential. Benzodiazepines have replaced barbiturates in recent years for several types of treatment.

Is Butalbital the Same as Fioricet?

Fioricet is not the same as butalbital, but it does contain this barbiturate compound. Fioricet is a brand-name drug containing butalbital, acetaminophen, and caffeine in one oral tablet or capsule. This medication is very similar to esgic, fiorinal, orbivan, repan, margesic, phrenilin, and phenobarbital, all of which contain butalbital and some form of pain reliever.

Is Butalbital Used for Anxiety?

Though it is used primarily to treat tension headaches, butalbital can also be prescribed to treat anxiety. This was once used as a common medication to treat this condition, but it has become less prescribed in favor of benzodiazepines, which are more widely used today.

What are the Possible Side Effects of Acetaminophen, Butalbital, and Caffeine?

In addition to those listed above, possible adverse effects of the combination drug of acetaminophen, butalbital, and caffeine include:

      • Liver damage or liver disease
      • Kidney disease
      • Abdominal pain
      • Irritability
      • Constipation
      • Nervousness
      • Tremors
      • Increased urination
      • Dark urine
      • Fainting
      • Confusion
      • Rapid heart rate
      • Difficulty sleeping

 

Fioricet Drug Interaction

Fioricet contains Butalbital, Acetaminophen, and caffeine.  A lot of other pain relievers contain Butalbital, Acetaminophen, and caffeine too.

I can only list some common over the counter medicines that contain Acetaminophen:  Actifed, Alka-Seltzer, Plus Liquid Gels, Anacin, Cepacol, Contac, Coricidin, Dayquil, Dimetapp, Dristan, Excedrin, Feverall …

Some prescriptions that contain acetaminophen are: Ultrace, Fioricet, Oxycodone, Endocet, Tylox …

You also must know what drugs contain Butalbital:  Bupap, Phrenilin, Tencon, Cephadyn; Fioricet, Esgic, Esgic-Plus; Fioricet with Codeine, Floricet with Codeine, Phrenilin with Caffeine and Codeine; Axotal; Fiorinal, Butalbital Compound, Farbital, Idenal; Fiorinal with Codeine, Fiorinal with Codeine III, Ascomp with Codeine, Fiortal with Codeine.

When you take more than one pain killer, you must read very carefully about their components.  Never exceed the max dosage of acetaminophen and butalbital of all the medicines you are taking.   Normally All the packages sent to you have the drug introduction and doctor names and phone number.  Read the drug introduction very carefully and never share the medicines with your sisters, your brothers,  your parents, or any friends. Always do not let the children touch the medicines.

Please donot drink any alcohol (Ethanol) with your Fioricet Because Ethanol together with acetaminophen will cause serious side effects that affect your liver, and Ethanol together with Butalbital will cause side effects of dizziness, drowsiness.

Please don’t take herb while you are taking Fioricet. Even Vitamins will have some interaction with Fioricet.

Be honest to place the current medicines you are taking in the health questionnaire  form. The doctor will check whether you are OK to take Fioricet.  If they think your current drugs or herbs have some interaction with Fioricet, they will phone you to discuss the situation with you. So please always leave us the correct phone number. We will never call you to promote you anything.

Most frequently checked interactions

View interaction reports for Fioricet (acetaminophen / butalbital / caffeine) and the medicines listed below.

    • Adderall (amphetamine / dextroamphetamine)
    • Advil (ibuprofen)
    • Ambien (zolpidem)
    • aspirin
    • Ativan (lorazepam)
    • baclofen
    • caffeine
    • clonazepam
    • codeine
    • Cymbalta (duloxetine)
    • Excedrin (acetaminophen / aspirin / caffeine)
    • Flexeril (cyclobenzaprine)
    • gabapentin
    • hydrocodone
    • ibuprofen
    • ibuprofen
    • Imitrex (sumatriptan)
    • Klonopin (clonazepam)
    • levothyroxine
    • Lexapro (escitalopram)
    • lisinopril
    • Lyrica (pregabalin)
    • meloxicam
    • naproxen
    • Norco (acetaminophen / hydrocodone)
    • omeprazole
    • oxycodone
    • Percocet (acetaminophen / oxycodone)
    • prednisone
    • Suboxone (buprenorphine / naloxone)
    • Topamax (topiramate)
    • tramadol
    • trazodone
    • Tylenol (acetaminophen)
    • Vitamin D3 (cholecalciferol)
    • Xanax (alprazolam)
    • Zofran (ondansetron)

Fioricet (acetaminophen / butalbital / caffeine) disease interactions

There are 25 disease interactions with Fioricet (acetaminophen / butalbital / caffeine) which include:

    • alcoholism
    • liver disease
    • acute alcohol intoxication
    • drug dependence
    • liver disease
    • porphyria
    • rash
    • respiratory depression
    • cardiac disease
    • hypertension
    • liver disease
    • PUD
    • PKU
    • adrenal insufficiency
    • depression
    • hematologic toxicity
    • osteomalacia
    • paradoxical reactions
    • cardiotoxicity
    • bipolar disorders
    • psychiatric disorders
    • psychotic disorders
    • renal dysfunction
    • seizure disorders
    • GERD

Other Prescription Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

    • Ethanol
    • Tobacco

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

    • Cabbage
    • Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse, history of or
  • Drug dependence, or history of or
  • Weakened physical condition—Use with caution. May increase risk for more serious side effects.
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
  • Porphyria (an enzyme problem)—Should not be used in patients with this condition.
  • Stomach problems—Use with caution. May make these conditions worse.

What is Fioricet and What is Fioricet Side Effects ?

Fioricet and Esgic are brand names of a combination of butalbital (a barbiturate), acetaminophen and caffeine which is indicated for the treatment of tension headaches, muscle contraction headaches and post-dural puncture headaches. Although not indicated, they are commonly used to treat migraines and other pain related ailments.

Fioricet® (Butalbital, Acetaminophen, and Caffeine Tablets USP) is supplied in tablet form for oral administration.

Each tablet contains the following active ingredients:
butalbital USP . . . . . . . . . . . .50 mg
acetaminophen USP . . . . . . 325 mg
caffeine USP . . . . . . . . . . . . .40 mg

Inactive Ingredients: crospovidone, FD&C Blue #1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid.

Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Before taking Fioricet

Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use Fioricet if you are allergic to acetaminophen, butalbital, or caffeine, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.

To make sure Fioricet is safe for you, tell your doctor if you have:

  • liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;
  • kidney disease;
  • asthma, sleep apnea, or other breathing disorder;
  • stomach ulcer or bleeding;
  • a history of skin rash caused by any medication;
  • a history of mental illness or suicidal thoughts; or
  • if you use medicine to prevent blood clots.

It is not known whether Fioricet will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for sever

How should I take Fioricet?

Take Fioricet exactly as prescribed. Follow all directions on your prescription label. Do not take more of this medication than recommended. An overdose can damage your liver or cause death. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Butalbital may be habit-forming. Never share Fioricet with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away Fioricet is against the law.

Take Fioricet with food or milk if it upsets your stomach.

Store Fioricet at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Butalbital is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Fioricet dosing information

Usual Adult Dose of Fioricet for Headache:

Acetaminophen 300 mg, butalbital 50 mg, and caffeine 40 mg:
1 or 2 capsule(s) orally every 4 hours as needed. Maximum daily dose: 6 doses.

Acetaminophen 325 mg, butalbital 50 mg, and caffeine 40 mg:
1 or 2 tablet(s), capsule(s), or tablespoonful(s) orally every 4 hours.
Maximum daily dose: 6 doses

Acetaminophen 500 mg, butalbital 50 mg, and caffeine 40 mg:
1 tablet or capsule orally every 4 hours.
Maximum daily dose: 6 doses

Acetaminophen 750 mg, butalbital 50 mg, and caffeine 40 mg:
1 tablet orally every 4 hours.
Maximum daily dose: 5 tablets

Usual Pediatric Dose of Fioricet for Headache:

12 years and older:
Acetaminophen 300 mg, butalbital 50 mg, and caffeine 40 mg:
1 or 2 capsule(s) orally every 4 hours as needed. Maximum daily dose: 6 doses.

What happens if I miss a dose?

Since this medicine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Fioricet can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include insomnia, restlessness, tremor, diarrhea, increased shallow breathing, uneven heartbeats, seizure (convulsions), or fainting.

What should I avoid while taking Fioricet?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

While you are taking this medication, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice.

Fioricet side effects

Get emergency medical help if you have signs of an allergic reaction to Fioricet: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Stop using this medicine and call your doctor at once if you have:

  • confusion, seizure (convulsions);
  • shortness of breath;
  • a light-headed feeling, like you might pass out; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common Fioricet side effects may include:

  • drowsiness, dizziness;
  • feeling anxious or restless;
  • drunk feeling; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Fioricet?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking Fioricet with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with acetaminophen, butalbital, and caffeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Fioricet only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.