Who cannot take fioricet ?

Fioricet is the most effective prescription for headache including tension headache, migraine headache and even cluster headache and neck pain. But you must understand when you cannot take fioricet.

If you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications. You can not use fioricet.

If you have taken an MAO inhibitor in the past 14 days, you can not use fioricet.

If you are Pregnant or Breastfeeding, you cannot use fioricet.

If you have high pressure, please only take fioricet after you consulted your doctors.

Who cannot Buy Fioricet Online ?

- If you have liver, kidney, or heart diseases, please donot take fioricet. Because fioricet contains barbiturate butalbital, it can cross the placental barrier;
- We donot suggest you order fioricet online if you are pregnant or or in breast feeding period. If you are pregnant, please go to your street doctors and let them to check whether you are OK to take fioricet;
- If you are addictive to alcohol or other pain killer medicines, please donot buy fioricet online, you must find a street doctor to solve your addictive first before you order fioricet, or buy fioricet online;
- You must complete the health questionnaires very carefull because the US licensed doctors and pharmacists will review your health questionnaires to approve your prescription or not;
- All online pharmacies share the same blacklist. If you have paid bounced checks to any online pharmacy and you will be blacklisted by all online pharmacies. You are not allowed to order Fioricet Online;
- We will not send you Fioricet or Gabapentin if you have suicide thoughts

For more detail fioricet prescription instruction, you can check Wiki Fioricet. The pharmacy will also send you a instruction on fioricet usage and introduction. Please be very careful to take the fioricet within the max dosage. Never exceed the max dosages. Or you will be seriously damaged.

What is Fioricet?

Fioricet contains a combination of acetaminophen, butalbital, and caffeine.

Each tablet contains the following active ingredients:
butalbital USP . . . . . . . . . . . .50 mg
acetaminophen USP . . . . . . 325 mg
caffeine USP . . . . . . . . . . . . .40 mg

Acetaminophen is a pain reliever and fever reducer.

Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache.

Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Fioricet is used to treat tension headaches that are caused by muscle contractions.

Is it safe to take fioricet while on oxycodone?

Is it safe to take fioricet while on oxycodone?
I just got my wisdom teeth out yesterday and they were bothering me so I took 3 of the 5mg oxycodones that I was prescribed. I have a migraine though and I cannot sleep. Would it be safe for me to take fioricet to help with the migraine?

Best answer:

Answer by John Doe
I do sometimes myself, but I wouldnt take more then one of each due to the amount of Acetaminophen.
Fioricet has 325mg of acetaminophen, and it depends on what type of oxycodone medicine your on, some contain 325mg, and some have 650mg’s, or if it’s oxycontin it wont have any acetaminophen at all, just try not to ecceed more then 650 mg of acetaminophen in a 3 hour period.

What do you think? Answer below!

Acetaminophen Mechanism of Action

Paracetamol (acetaminophen) is generally considered to be a weak inhibitor of the synthesis of prostaglandins (PGs). However, the in vivo effects of paracetamol are similar to those of the selective cyclooxygenase-2 (COX-2) inhibitors. Paracetamol also decreases PG concentrations in vivo, but, unlike the selective COX-2 inhibitors, paracetamol does not suppress the inflammation of rheumatoid arthritis.

It does, however, decrease swelling after oral surgery in humans and suppresses inflammation in rats and mice. Paracetamol is a weak inhibitor of PG synthesis of COX-1 and COX-2 in broken cell systems, but, by contrast, therapeutic concentrations of paracetamol inhibit PG synthesis in intact cells in vitro when the levels of the substrate arachidonic acid are low (less than about 5 mumol/L).

When the levels of arachidonic acid are low, PGs are synthesized largely by COX-2 in cells that contain both COX-1 and COX-2. Thus, the apparent selectivity of paracetamol may be due to inhibition of COX-2-dependent pathways that are proceeding at low rates.

This hypothesis is consistent with the similar pharmacological effects of paracetamol and the selective COX-2 inhibitors. COX-3, a splice variant of COX-1, has been suggested to be the site of action of paracetamol, but genomic and kinetic analysis indicates that this selective interaction is unlikely to be clinically relevant.

There is considerable evidence that the analgesic effect of paracetamol is central and is due to activation of descending serotonergic pathways, but its primary site of action may still be inhibition of PG synthesis.

The action of paracetamol at a molecular level is unclear but could be related to the production of reactive metabolites by the peroxidase function of COX-2, which could deplete glutathione, a cofactor of enzymes such as PGE synthase.